PGMS Propylene glycol monostearate CAS 1323-39-3

A non-ionic, white powder or flake, which is insoluble with water, but soluble with ethanol and organic solvents.

About PGMS Propylene glycol monostearate: 

Physical property

Propylene glycol monostearate has a high melting point, usually between 68 and 72°C. Its appearance is a fine white powder or scaly solid, with a fat smell and odorless. The relative density is 0.89, insoluble in water but soluble in ethanol, ether, and other organic solvents. Propylene glycol monostearate has good dispersibility, wettability, and emulsifying stability and is widely used in cosmetics, food, and medicine.

Chemical properties

The chemical properties of propylene glycol monostearate are relatively stable, but oxidation, hydrolysis and other reactions can occur under certain conditions. It has ester and alcohol groups, can participate in esterification, etherification, acetal, and other reactions, and is an important raw material for synthesizing other organic compounds. Under acidic conditions, propylene glycol monostearate can react with carboxylic anhydride to form ester compounds. Under alkaline conditions, it can react with carboxylic acids or acid anhydrides to form salt compounds. In addition, propylene glycol monostearate can also be esterified with alcohol to produce ester compounds.

Surface activity

Propylene glycol monostearate has surface activity, which can reduce the surface tension of the liquid and produce wetting, emulsification, foaming, and other functions. These properties make propylene glycol monostearate widely used in cosmetics, food, medicine and other fields. In cosmetics, propylene glycol monostearate can be used as an emulsifier, stabilizer, thickener, etc., to improve product stability and use effect. In the food industry, it can be used as an emulsifier, anti-splash agent, etc., to improve the taste and stability of food. In drugs, propylene glycol monostearate can prepare ointment, suppository, etc., to moisturize the skin and relieve drug irritation.

Security

Propylene glycol monostearate is a safe and reliable chemical substance widely used in various fields. According to several toxicological studies, propylene glycol monostearate does not cause harm to the human body when used under normal conditions. However, due to its irritability, appropriate protective measures should be taken when in contact, such as wearing personal protective equipment such as gloves and masks. In addition, excessive intake of propylene glycol monostearate may have a certain irritating effect on the digestive system, causing uncomfortable symptoms such as diarrhea. Therefore, the use of propylene glycol monostearate should be carried out by the recommended dosage and conditions of use.

 Technical Parameters of PGMS (Propylene glycol Monostearate):

Applications of PGMS Propylene glycol monostearate  : 

Cosmetics field

Propylene glycol monostearate is an important raw material in cosmetics, mainly used as an emulsifier, emollient, and thickening agent. It can improve the stability of the product, improve the effect of use, and make cosmetics more in line with market demand.

Lotions and creams: Propylene glycol monostearate can be used as an emulsifier to mix water and oil to produce stable, delicate lotions and creams. It can improve the product's moisturizing degree and moisturizing effect, providing good protection for the skin.

Makeup products: In lipstick, eyeshadow, foundation and other makeup products, propylene glycol monostearate can be used as an emollient and thickening agent to increase the smoothness and applicability of the product and improve the feeling of use.

Shampoos and body wash: In shampoos and body washes, propylene glycol monostearate can be used as a foam stabilizer and emollient to increase the foam richness of the product and improve the comfort of use.

Food industry

In the food industry, propylene glycol monostearate is mainly used to prepare food emulsifiers and stabilizers to improve the taste and stability of food.

Dairy products: In dairy products, propylene glycol monostearate can be used as an emulsifier and stabilizer to improve the taste and stability of the product. For example, adding propylene glycol monostearate to yogurt, cheese and other products can make it more delicate and smooth.

Beverage: In the beverage, propylene glycol monostearate can be used as a suspension agent and stabilizer so that the particles or pulp and other substances in the beverage are uniformly suspended, improving the quality and stability of the product.

Confectionery and chocolate: In confectionery and chocolate, propylene glycol monostearate can be used as an emollient and softener to enhance the taste and texture of the product. At the same time, it can also prevent candy and chocolate from melting under high-temperature conditions, improving their stability.

Pharmaceutical field

In medicine, propylene glycol monostearate is mainly used to prepare ointment, suppositories, and other drugs, which play a role in moisturizing the skin and alleviating drug irritation.

Ointment: Propylene glycol monostearate can be used as a matrix component to disperse the drug in the matrix evenly to prepare a cream that is easy to apply and has good adhesion. It can moisturize the skin, relieve drug irritation, and improve the comfort of patients taking drugs.

Suppositories: In suppositories, propylene glycol monostearate acts as a lubricant and softener, making it easier to insert suppositories in places such as the anus or vagina. At the same time, it can also increase the drug's solubility and stability and improve the suppositories' therapeutic effect.

Oral medicine: In oral medicine, propylene glycol monostearate can be used as a lubricant and protective agent for oral mucosa to promote the repair and healing of oral mucosa. For example, the addition of propylene glycol monostearate to oral ulcer film can play a role in reducing pain and promoting healing.

Production Method of PGMS Propylene glycol monostearate  : 

Chemical synthesis

Chemical synthesis is a common method to produce propylene glycol monostearate. The method converts the raw material into the target product through chemical reactions. The following are the specific steps of chemical synthesis:

Preparation of raw materials: Prepare the required raw materials, such as acrolein, formic acid, formaldehyde, etc. These raw materials should meet specifications to ensure the quality of propylene glycol monostearate produced.

Oxidation reaction: Acrolein and formic acid are added to the reactor, and oxidation reaction is carried out under a certain temperature and pressure to produce propylene glycol. The reaction can use different oxidants, such as nitric acid, potassium permanganate, etc.

Hydrogenation reaction: The propylene glycol generated in the previous step is hydrogenated under a catalyst, so the alkene bond is converted into an alkane bond. The reaction can be carried out at a certain temperature and pressure using hydrogen as a reducing agent.

Esterification reaction: The hydrogenated propylene glycol is esterified with stearic acid under certain conditions to produce propylene glycol monostearate. The reaction can use sulfuric acid or other acidic catalysts to promote the reaction.

Separation and purification: The resulting propylene glycol monostearate is separated and purified after the reaction. Usually, the products are separated by distillation, crystallization, and other methods and then refined and dried to obtain high-purity monostearate propylene glycol.

The advantages of chemical synthesis are a mature process, high yield, and strong applicability. The molecular weight and other properties of propylene glycol monostearate can be controlled by adjusting the reaction conditions and the proportion of raw materials. However, there are some challenges and limitations to chemical synthesis. First, the method requires multiple raw materials and catalysts, increasing the cost and complexity of production. Secondly, some reaction steps need to strictly control parameters such as temperature and pressure, which have high requirements for equipment. In addition, chemical synthesis may produce waste and by-products, which have a certain impact on the environment.

Direct esterification method

Direct esterification is a relatively simple method to prepare propylene glycol monostearate. Propylene glycol monostearate is prepared by directly esterifying stearic acid and ethylene oxide, avoiding using multiple raw materials and catalysts. The following are the specific steps of the direct esterification process:

Add stearic acid and ethylene oxide to the reactor and stir well.

Under certain temperatures and pressure, stearic acid and ethylene oxide were esterified to produce propylene glycol monostearate.

After the reaction, propylene glycol monostearate was separated and purified. Usually, the products are separated by distillation, crystallization, and other methods and then refined and dried to obtain high-purity monostearate propylene glycol.

The advantages of direct esterification are that it is simple to process, safe, and has environmental protection. This method avoids using multiple raw materials and catalysts, reducing production costs and environmental impact. In addition, the reaction conditions of the direct esterification method are relatively mild, and parameters such as temperature and pressure need to be controlled to ensure that the reaction proceeds smoothly and a high-purity product is obtained. However, there are some challenges and limitations to direct esterification. First, the method requires using a large amount of ethylene oxide as a raw material, so there is a certain impact on the supply and cost of raw materials. Secondly, the reaction rate of the direct esterification method is slow, and the reaction time is longer, which reduces the production efficiency. In addition, the method needs to be further optimized, and the yield needs to be increased to meet market demand.

Packing and shipping of Propylene Glycol Monostearate PGMS:

The packaging we offer is dependent on the quantity of PGMS Propylene monostearate.
 PGMS Propylene glycol monostearate packing: 1kg per bottle, 25kg per barrel, or 200kg per barrel.
 PGMS Propylene glycol monostearate shipping: The shipment can be made by air, sea or express as soon after payment as possible.

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